Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis D Groza, S Gehrig, P Kudela, M Holcmann, C Pirker, C Dinhof, ... Oncoimmunology 7 (5), e1424676, 2018 | 42 | 2018 |
Structure–activity relationships of triple-action platinum (IV) Prodrugs with albumin-binding properties and immunomodulating ligands P Fronik, I Poetsch, A Kastner, T Mendrina, S Hager, K Hohenwallner, ... Journal of Medicinal Chemistry 64 (16), 12132-12151, 2021 | 40 | 2021 |
Copper-catalyzed glutathione oxidation is accelerated by the anticancer thiosemicarbazone Dp44mT and further boosted at lower pH E Falcone, AG Ritacca, S Hager, H Schueffl, B Vileno, Y El Khoury, ... Journal of the American Chemical Society 144 (32), 14758-14768, 2022 | 39 | 2022 |
Albumin-targeting of an oxaliplatin-releasing platinum (iv) prodrug results in pronounced anticancer activity due to endocytotic drug uptake in vivo H Schueffl, S Theiner, G Hermann, J Mayr, P Fronik, D Groza, ... Chemical Science 12 (38), 12587-12599, 2021 | 27 | 2021 |
Improving the stability of EGFR inhibitor cobalt (III) prodrugs M Mathuber, H Schueffl, O Dömötör, C Karnthaler, EA Enyedy, ... Inorganic Chemistry 59 (23), 17794-17810, 2020 | 23 | 2020 |
CD47-targeted cancer immunogene therapy: Secreted SIRPα-Fc fusion protein eradicates tumors by macrophage and NK cell activation M Billerhart, M Schönhofer, H Schueffl, W Polzer, J Pichler, S Decker, ... Molecular Therapy-Oncolytics 23, 192-204, 2021 | 18 | 2021 |
Oral Anticancer Heterobimetallic PtIV−AuI Complexes Show High In Vivo Activity and Low Toxicity T Babu, H Ghareeb, U Basu, H Schueffl, S Theiner, P Heffeter, ... Angewandte Chemie 135 (10), e202217233, 2023 | 16 | 2023 |
Development and biological investigations of hypoxia-sensitive prodrugs of the tyrosine kinase inhibitor crizotinib B Bielec, H Schueffl, A Terenzi, W Berger, P Heffeter, BK Keppler, ... Bioorganic chemistry 99, 103778, 2020 | 16 | 2020 |
Position-selective synthesis and biological evaluation of four isomeric A-ring amino derivatives of the alkaloid luotonin A A Ibric, S Eckerstorfer, M Eder, I Louko, L Tunjic, P Heffeter, HH Schueffl, ... Molecules 24 (4), 716, 2019 | 15 | 2019 |
Degradable Bottlebrush Polypeptides and the Impact of their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo P Strasser, B Montsch, S Weiss, H Sami, C Kugler, S Hager, H Schueffl, ... Small, 2300767, 2023 | 7 | 2023 |
Insertion of (Bioactive) Equatorial Ligands into Platinum (IV) Complexes A Kastner, H Schueffl, PA Yassemipour, BK Keppler, P Heffeter, ... Angewandte Chemie International Edition 62 (46), e202311468, 2023 | 5 | 2023 |
Destabilization of FoxM1 and inhibition of topoisomerase I contribute to cytotoxicity of prenylated xanthones isolated from Metaxya rostrata E Mittermair, H Schueffl, P Heffeter, L Krenn, B Marian Planta Medica 86 (15), 1073-1079, 2020 | 5 | 2020 |
A-ring and E-ring modifications of the cytotoxic alkaloid Luotonin A: Synthesis, computational and biological studies A Ibric, V Battisti, S Deckardt, AV Haller, C Lee, C Prötsch, T Langer, ... Bioorganic & Medicinal Chemistry 28 (9), 115443, 2020 | 5 | 2020 |
Influence of the Fatty Acid Metabolism on the Mode of Action of a Cisplatin (IV) Complex with Phenylbutyrate as Axial Ligands T Mendrina, I Poetsch, H Schueffl, D Baier, C Pirker, A Ries, BK Keppler, ... Pharmaceutics 15 (2), 677, 2023 | 4 | 2023 |
A novel EGFR inhibitor acts as potent tool for hypoxia-activated prodrug systems and exerts strong synergistic activity with VEGFR inhibition in vitro and in vivo M Caban, B Koblmueller, D Groza, HH Schueffl, A Terenzi, A Tolios, ... Cancer Letters 565, 216237, 2023 | 3 | 2023 |
Quantification of ferritin-bound iron in murine samples for Alzheimer’s disease studies using species-specific isotope dilution mass spectrometry A Tchaikovsky, A Schoeberl, H Schueffl, A Raab, S Emin, A Slany, ... Metrologia 57 (4), 042101, 2020 | 3 | 2020 |
Methylated Xanthones from the Rootlets of Metaxya rostrata Display Cytotoxic Activity in Colorectal Cancer Cells E Mittermair, H Kählig, A Tahir, S Rindler, X Hudec, H Schueffl, P Heffeter, ... Molecules 25 (19), 4449, 2020 | 1 | 2020 |
Metal-Based Prodrugs Activated by Cancer-Specific Stimuli M Dijkstra, H Schueffl, I Poetsch, P Heffeter, CR Kowol Targeted Metallo-Drugs, 1-38, 2023 | | 2023 |
The calcium-sensing receptor modulates the prostaglandin E2 pathway in intestinal inflammation V Gushchina, N Kupper, M Schwarzkopf, G Frisch, K Piatek, C Aigner, ... Frontiers in Pharmacology 14, 1151144, 2023 | | 2023 |