Suivre
Hemma Schueffl
Hemma Schueffl
Center for Cancer Research, Medical University of Vienna
Adresse e-mail validée de meduniwien.ac.at
Titre
Citée par
Citée par
Année
Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis
D Groza, S Gehrig, P Kudela, M Holcmann, C Pirker, C Dinhof, ...
Oncoimmunology 7 (5), e1424676, 2018
422018
Structure–activity relationships of triple-action platinum (IV) Prodrugs with albumin-binding properties and immunomodulating ligands
P Fronik, I Poetsch, A Kastner, T Mendrina, S Hager, K Hohenwallner, ...
Journal of Medicinal Chemistry 64 (16), 12132-12151, 2021
402021
Copper-catalyzed glutathione oxidation is accelerated by the anticancer thiosemicarbazone Dp44mT and further boosted at lower pH
E Falcone, AG Ritacca, S Hager, H Schueffl, B Vileno, Y El Khoury, ...
Journal of the American Chemical Society 144 (32), 14758-14768, 2022
392022
Albumin-targeting of an oxaliplatin-releasing platinum (iv) prodrug results in pronounced anticancer activity due to endocytotic drug uptake in vivo
H Schueffl, S Theiner, G Hermann, J Mayr, P Fronik, D Groza, ...
Chemical Science 12 (38), 12587-12599, 2021
272021
Improving the stability of EGFR inhibitor cobalt (III) prodrugs
M Mathuber, H Schueffl, O Dömötör, C Karnthaler, EA Enyedy, ...
Inorganic Chemistry 59 (23), 17794-17810, 2020
232020
CD47-targeted cancer immunogene therapy: Secreted SIRPα-Fc fusion protein eradicates tumors by macrophage and NK cell activation
M Billerhart, M Schönhofer, H Schueffl, W Polzer, J Pichler, S Decker, ...
Molecular Therapy-Oncolytics 23, 192-204, 2021
182021
Oral Anticancer Heterobimetallic PtIV−AuI Complexes Show High In Vivo Activity and Low Toxicity
T Babu, H Ghareeb, U Basu, H Schueffl, S Theiner, P Heffeter, ...
Angewandte Chemie 135 (10), e202217233, 2023
162023
Development and biological investigations of hypoxia-sensitive prodrugs of the tyrosine kinase inhibitor crizotinib
B Bielec, H Schueffl, A Terenzi, W Berger, P Heffeter, BK Keppler, ...
Bioorganic chemistry 99, 103778, 2020
162020
Position-selective synthesis and biological evaluation of four isomeric A-ring amino derivatives of the alkaloid luotonin A
A Ibric, S Eckerstorfer, M Eder, I Louko, L Tunjic, P Heffeter, HH Schueffl, ...
Molecules 24 (4), 716, 2019
152019
Degradable Bottlebrush Polypeptides and the Impact of their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo
P Strasser, B Montsch, S Weiss, H Sami, C Kugler, S Hager, H Schueffl, ...
Small, 2300767, 2023
72023
Insertion of (Bioactive) Equatorial Ligands into Platinum (IV) Complexes
A Kastner, H Schueffl, PA Yassemipour, BK Keppler, P Heffeter, ...
Angewandte Chemie International Edition 62 (46), e202311468, 2023
52023
Destabilization of FoxM1 and inhibition of topoisomerase I contribute to cytotoxicity of prenylated xanthones isolated from Metaxya rostrata
E Mittermair, H Schueffl, P Heffeter, L Krenn, B Marian
Planta Medica 86 (15), 1073-1079, 2020
52020
A-ring and E-ring modifications of the cytotoxic alkaloid Luotonin A: Synthesis, computational and biological studies
A Ibric, V Battisti, S Deckardt, AV Haller, C Lee, C Prötsch, T Langer, ...
Bioorganic & Medicinal Chemistry 28 (9), 115443, 2020
52020
Influence of the Fatty Acid Metabolism on the Mode of Action of a Cisplatin (IV) Complex with Phenylbutyrate as Axial Ligands
T Mendrina, I Poetsch, H Schueffl, D Baier, C Pirker, A Ries, BK Keppler, ...
Pharmaceutics 15 (2), 677, 2023
42023
A novel EGFR inhibitor acts as potent tool for hypoxia-activated prodrug systems and exerts strong synergistic activity with VEGFR inhibition in vitro and in vivo
M Caban, B Koblmueller, D Groza, HH Schueffl, A Terenzi, A Tolios, ...
Cancer Letters 565, 216237, 2023
32023
Quantification of ferritin-bound iron in murine samples for Alzheimer’s disease studies using species-specific isotope dilution mass spectrometry
A Tchaikovsky, A Schoeberl, H Schueffl, A Raab, S Emin, A Slany, ...
Metrologia 57 (4), 042101, 2020
32020
Methylated Xanthones from the Rootlets of Metaxya rostrata Display Cytotoxic Activity in Colorectal Cancer Cells
E Mittermair, H Kählig, A Tahir, S Rindler, X Hudec, H Schueffl, P Heffeter, ...
Molecules 25 (19), 4449, 2020
12020
Metal-Based Prodrugs Activated by Cancer-Specific Stimuli
M Dijkstra, H Schueffl, I Poetsch, P Heffeter, CR Kowol
Targeted Metallo-Drugs, 1-38, 2023
2023
The calcium-sensing receptor modulates the prostaglandin E2 pathway in intestinal inflammation
V Gushchina, N Kupper, M Schwarzkopf, G Frisch, K Piatek, C Aigner, ...
Frontiers in Pharmacology 14, 1151144, 2023
2023
Le système ne peut pas réaliser cette opération maintenant. Veuillez réessayer plus tard.
Articles 1–19