| Transferrin receptor is a specific ferroptosis marker H Feng, K Schorpp, J Jin, CE Yozwiak, BG Hoffstrom, AM Decker, ... Cell reports 30 (10), 3411-3423. e7, 2020 | 579 | 2020 |
| Multivalent small-molecule pan-RAS inhibitors ME Welsch, A Kaplan, JM Chambers, ME Stokes, PH Bos, A Zask, ... Cell 168 (5), 878-889. e29, 2017 | 272 | 2017 |
| MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling D Venkatesh, NA O'Brien, F Zandkarimi, DR Tong, ME Stokes, DE Dunn, ... Genes & development 34 (7-8), 526-543, 2020 | 210 | 2020 |
| Detection of parasitic plant suicide germination compounds using a high-throughput Arabidopsis HTL/KAI2 strigolactone perception system S Toh, D Holbrook-Smith, ME Stokes, Y Tsuchiya, P McCourt Chemistry & biology 21 (8), 988-998, 2014 | 134 | 2014 |
| Interplay between sucrose and folate modulates auxin signaling in Arabidopsis ME Stokes, A Chattopadhyay, O Wilkins, E Nambara, MM Campbell Plant Physiology 162 (3), 1552-1565, 2013 | 96 | 2013 |
| Copper-binding small molecule induces oxidative stress and cell-cycle arrest in glioblastoma-patient-derived cells K Shimada, E Reznik, ME Stokes, L Krishnamoorthy, PH Bos, Y Song, ... Cell chemical biology 25 (5), 585-594. e7, 2018 | 82 | 2018 |
| Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19 H Liu, S Iketani, A Zask, N Khanizeman, E Bednarova, F Forouhar, ... Nature communications 13 (1), 1891, 2022 | 68 | 2022 |
| Towards personalized agriculture: what chemical genomics can bring to plant biotechnology ME Stokes, P McCourt Frontiers in Plant Science 5, 344, 2014 | 18 | 2014 |
| Transferrin receptor is a specific ferroptosis marker. Cell Rep. 30, 3411–3423. e7 H Feng, K Schorpp, J Jin, CE Yozwiak, BG Hoffstrom, AM Decker, ... | 17 | 2020 |
| A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response–Dependent Survival of Quiescent Cancer Cells V Calvo, W Zheng, A Adam-Artigues, KA Staschke, X Huang, JF Cheung, ... Clinical Cancer Research 29 (24), 5155-5172, 2023 | 6 | 2023 |
| PERK inhibition by HC-5404 sensitizes renal cell carcinoma tumor models to antiangiogenic tyrosine kinase inhibitors ME Stokes, V Calvo, S Fujisawa, C Dudgeon, S Huang, N Ballal, L Shen, ... Clinical Cancer Research 29 (23), 4870-4882, 2023 | 6 | 2023 |
| Optimization of a novel mandelamide-derived pyrrolopyrimidine series of PERK inhibitors ME Stokes, MD Surman, V Calvo, D Surguladze, AH Li, J Gasparek, ... Pharmaceutics 14 (10), 2233, 2022 | 5 | 2022 |
| Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers ME Stokes, A Vasciaveo, JC Small, A Zask, E Reznik, N Smith, Q Wang, ... Cell Chemical Biology 31 (4), 805-819. e9, 2024 | 3 | 2024 |
| Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation ME Stokes, JC Small, A Vasciaveo, K Shimada, T Hirschhorn, A Califano, ... Scientific Reports 10 (1), 10748, 2020 | 3 | 2020 |
| Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells AP Sobinoff, S Di Maro, RRJ Low, R Benedetti, S Tomassi, A D'Aniello, ... Cell Chemical Biology 30 (12), 1652-1665. e6, 2023 | 2 | 2023 |
| HC-7366, a potent GCN2 activator, complements belzutifan, a HIF-2⍺ antagonist, by providing combination benefit in belzutifan-sensitive models and monotherapy activity in … ME Stokes, F Tameire, P Wojnarowicz, S Fujisawa, C Dudgeon, S Huang, ... Cancer Research 84 (6_Supplement), 4615-4615, 2024 | 1 | 2024 |
| Activation of GCN2 by HC-7366 results in significant anti-tumor efficacy As monotherapy and overcomes resistance mechanisms when combined with Venetoclax in AML F Tameire, N Collette, S Fujisawaa, K Bieging-Rolett, C Dudgeon, ... Blood 142, 2943, 2023 | 1 | 2023 |
| Erratum: Detection of parasitic plant suicide germination compounds using a high-throughput Arabidopsis HTL/KAI2 strigolactone perception system (Chemistry & Biology (2014) 21 … S Toh, D Holbrook-Smith, ME Stokes, Y Tsuchiya, P McCourt Chemistry and Biology 21 (9), e1253-e1253, 2014 | 1 | 2014 |
| Inhibition of the eukaryotic initiation factor-2-α kinase PERK decreases risk of autoimmune diabetes in mice C Muralidharan, F Huang, JR Enriquez, JE Wang, JB Nelson, T Nargis, ... The Journal of Clinical Investigation, 2024 | | 2024 |
| A multicenter, open-label, phase 1a study of HC-5404 in patients with advanced solid tumors. AZ Dudek, J O'Shaughnessy, SA Piha-Paul, D Uprety, BL Kitchens, ... Journal of Clinical Oncology 42 (16_suppl), e15118-e15118, 2024 | | 2024 |
