Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice C Guerra, AJ Schuhmacher, M Cañamero, PJ Grippo, L Verdaguer, ... Cancer cell 11 (3), 291-302, 2007 | 1382 | 2007 |
Cdk1 is sufficient to drive the mammalian cell cycle D Santamaría, C Barrière, A Cerqueira, S Hunt, C Tardy, K Newton, ... Nature 448 (7155), 811-815, 2007 | 1251 | 2007 |
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice S Ortega, I Prieto, J Odajima, A Martín, P Dubus, R Sotillo, JL Barbero, ... Nature genetics 35 (1), 25-31, 2003 | 1000 | 2003 |
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6 M Malumbres, R Sotillo, D Santamarı́a, J Galán, A Cerezo, S Ortega, ... Cell 118 (4), 493-504, 2004 | 985 | 2004 |
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia SG Rane, P Dubus, RV Mettus, EJ Galbreath, G Boden, EP Reddy, ... Nature genetics 22 (1), 44-52, 1999 | 897 | 1999 |
Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context C Guerra, N Mijimolle, A Dhawahir, P Dubus, M Barradas, M Serrano, ... Cancer cell 4 (2), 111-120, 2003 | 664 | 2003 |
Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome A Briot, C Deraison, M Lacroix, C Bonnart, A Robin, C Besson, P Dubus, ... Journal of Experimental Medicine 206 (5), 1135-1147, 2009 | 564 | 2009 |
A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma M Puyol, A Martín, P Dubus, F Mulero, P Pizcueta, G Khan, C Guerra, ... Cancer cell 18 (1), 63-73, 2010 | 504 | 2010 |
Genomic stability and tumour suppression by the APC/C cofactor Cdh1 I García-Higuera, E Manchado, P Dubus, M Cañamero, J Méndez, ... Nature cell biology 10 (7), 802-811, 2008 | 389 | 2008 |
c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma RB Blasco, S Francoz, D Santamaría, M Canamero, P Dubus, J Charron, ... Cancer cell 19 (5), 652-663, 2011 | 338 | 2011 |
Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27Kip1 and p21Cip1 A Martín, J Odajima, SL Hunt, P Dubus, S Ortega, M Malumbres, ... Cancer cell 7 (6), 591-598, 2005 | 266 | 2005 |
Wide spectrum of tumors in knock‐in mice carrying a Cdk4 protein insensitive to INK4 inhibitors R Sotillo, P Dubus, J Martn, E de la Cueva, S Ortega, M Malumbres, ... The EMBO journal, 2001 | 249 | 2001 |
Expression of neurotrophins and their receptors in human bone marrow E Labouyrie, P Dubus, A Groppi, FX Mahon, J Ferrer, M Parrens, ... The American journal of pathology 154 (2), 405-415, 1999 | 244 | 1999 |
Invasive melanoma in Cdk4-targeted mice R Sotillo, JF García, S Ortega, J Martín, P Dubus, M Barbacid, ... Proceedings of the National Academy of Sciences 98 (23), 13312-13317, 2001 | 207 | 2001 |
Cdk4 promotes adipogenesis through PPARγ activation A Abella, P Dubus, M Malumbres, SG Rane, H Kiyokawa, A Sicard, ... Cell metabolism 2 (4), 239-249, 2005 | 192 | 2005 |
A comparative analysis of FISH, RT-PCR, PCR, and immunohistochemistry for the diagnosis of mantle cell lymphomas MA Belaud-Rotureau, M Parrens, P Dubus, JC Garroste, A de Mascarel, ... Modern Pathology 15 (5), 517-525, 2002 | 184 | 2002 |
Characterization of biomarkers of tumorigenic and chemoresistant cancer stem cells in human gastric carcinoma PH Nguyen, J Giraud, L Chambonnier, P Dubus, L Wittkop, G Belleannée, ... Clinical Cancer Research 23 (6), 1586-1597, 2017 | 170 | 2017 |
Mice thrive without Cdk4 and Cdk2 C Barrière, D Santamaría, A Cerqueira, J Galán, A Martín, S Ortega, ... Molecular oncology 1 (1), 72-83, 2007 | 162 | 2007 |
Genetic rescue of Cdk4 null mice restores pancreatic β-cell proliferation but not homeostatic cell number J Martín, SL Hunt, P Dubus, R Sotillo, F Nehme-Pelluard, MA Magnuson, ... Oncogene 22 (34), 5261-5269, 2003 | 161 | 2003 |
Helicobacter pylori infection recruits bone marrow− derived cells that participate in gastric preneoplasia in mice C Varon, P Dubus, F Mazurier, C Asencio, L Chambonnier, J Ferrand, ... Gastroenterology 142 (2), 281-291, 2012 | 149 | 2012 |