Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2381 | 2019 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 948 | 2017 |
The etiology of poststroke depression: a review of the literature and a new hypothesis involving inflammatory cytokines G Spalletta, P Bossu, A Ciaramella, P Bria, C Caltagirone, RG Robinson Molecular psychiatry 11 (11), 984-991, 2006 | 397 | 2006 |
Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) patients are characterized by increased BDNF serum levels F Angelucci, G Spalletta, F Iulio, A Ciaramella, F Salani, AE Varsi, ... Current Alzheimer Research 7 (1), 15-20, 2010 | 239 | 2010 |
IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease P Bossu, D Neumann, E Del Giudice, A Ciaramella, I Gloaguen, ... Proceedings of the National Academy of Sciences 100 (24), 14181-14186, 2003 | 164 | 2003 |
Interleukin-18 produced by peripheral blood cells is increased in Alzheimer’s disease and correlates with cognitive impairment P Bossu, A Ciaramella, F Salani, F Bizzoni, E Varsi, F Di Iulio, F Giubilei, ... Brain, behavior, and immunity 22 (4), 487-492, 2008 | 112 | 2008 |
Interleukin-18, from neuroinflammation to Alzheimer's disease P Bossù, A Ciaramella, F Salani, D Vanni, I Palladino, C Caltagirone, ... Current pharmaceutical design 16 (38), 4213-4224, 2010 | 102 | 2010 |
Induction of apoptosis and release of interleukin-1β by cell wall-associated 19-kDa lipoprotein during the course of mycobacterial infection A Ciaramella, A Cavone, MB Santucci, SK Garg, N Sanarico, M Bocchino, ... The Journal of infectious diseases 190 (6), 1167-76, 2004 | 80 | 2004 |
Increased levels of serum MAP-2 at 6-months correlate with improved outcome in survivors of severe traumatic brain injury S Mondello, A Gabrielli, S Catani, M D’Ippolito, A Jeromin, A Ciaramella, ... Brain injury 26 (13-14), 1629-1635, 2012 | 75 | 2012 |
Interleukin 18 gene polymorphisms predict risk and outcome of Alzheimer’s disease P Bossù, A Ciaramella, ML Moro, L Bellincampi, S Bernardini, G Federici, ... Journal of Neurology, Neurosurgery & Psychiatry 78 (8), 807-811, 2007 | 72 | 2007 |
Increased pro-inflammatory response by dendritic cells from patients with Alzheimer's disease A Ciaramella, F Bizzoni, F Salani, D Vanni, G Spalletta, N Sanarico, ... Journal of Alzheimer's Disease 19 (2), 559-572, 2010 | 64 | 2010 |
Human monocyte-derived dendritic cells differentiated in the presence of IL-2 produce proinflammatory cytokines and prime Th1 immune response N Sanarico, A Ciaramella, A Sacchi, D Bernasconi, P Bossu, F Mariani, ... Journal of leukocyte biology 80 (3), 555-562, 2006 | 64 | 2006 |
Proinflammatory Cytokines in the Course of Mycobacteriumtuberculosis–Induced Apoptosis in Monocytes/Macrophages A Ciaramella, A Cavone, MB Santucci, M Amicosante, A Martino, ... The Journal of infectious diseases 186 (9), 1277-1282, 2002 | 62 | 2002 |
Macrophage Response to Mycobacterium tuberculosis During HIV Infection Relationships Between Macrophage Activation and Apoptosis. F Mariani, D Goletti, A Ciaramella, A Martino, V Colizzi, M Fraziano Current molecular medicine 1 (2), 209-216, 2001 | 62 | 2001 |
Mycobacterial 19-kDa lipoprotein mediates Mycobacterium tuberculosis-induced apoptosis in monocytes/macrophages at early stages of infection A Ciaramella, A Martino, R Cicconi, V Colizzi, M Fraziano Cell Death & Differentiation 7 (12), 1270-1272, 2000 | 58 | 2000 |
Dendritic cells derived from BCG-infected precursors induce Th2-like immune response A Martino, A Sacchi, N Sanarico, F Spadaro, C Ramoni, A Ciaramella, ... Journal of leukocyte biology 76 (4), 827-834, 2004 | 53 | 2004 |
Blood dendritic cell frequency declines in idiopathic Parkinson’s disease and is associated with motor symptom severity A Ciaramella, F Salani, F Bizzoni, FE Pontieri, A Stefani, M Pierantozzi, ... PLoS One 8 (6), e65352, 2013 | 50 | 2013 |
Lymphocytes from autoimmune MRL lpr/lpr mice are hyperresponsive to IL-18 and overexpress the IL-18 receptor accessory chain D Neumann, E Del Giudice, A Ciaramella, D Boraschi, P Bossu The Journal of Immunology 166 (6), 3757-3762, 2001 | 49 | 2001 |
Myeloid dendritic cells are decreased in peripheral blood of Alzheimer’s disease patients in association with disease progression and severity of depressive symptoms A Ciaramella, F Salani, F Bizzoni, MD Orfei, C Caltagirone, G Spalletta, ... Journal of Neuroinflammation 13, 1-11, 2016 | 48 | 2016 |
Myeloid dendritic cells are potential players in human neurodegenerative diseases P Bossù, G Spalletta, C Caltagirone, A Ciaramella Frontiers in immunology 6, 632, 2015 | 45 | 2015 |