Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction. IK Tatsumi S, Ishii K, Amizuka N, Li M, Kobayashi T, Kohno K, Ito M, Takeshita S Cell Metabolism 5, 464-475, 0 | 2109* | |
Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss F Thorel, V Népote, I Avril, K Kohno, R Desgraz, S Chera, PL Herrera Nature 464 (7292), 1149-1154, 2010 | 1320 | 2010 |
The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche Y Omatsu, T Sugiyama, H Kohara, G Kondoh, N Fujii, K Kohno, ... Immunity 33 (3), 387-399, 2010 | 944 | 2010 |
Podocyte depletion causes glomerulosclerosis: Diphtheria toxin–induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene BL Wharram, M Goyal, JE Wiggins, SK Sanden, S Hussain, WE Filipiak, ... Journal of the American Society of Nephrology 16 (10), 2941-2952, 2005 | 856 | 2005 |
Paneth cells as a site of origin for intestinal inflammation TE Adolph, MF Tomczak, L Niederreiter, HJ Ko, J Böck, E Martinez-Naves, ... Nature 503 (7475), 272-276, 2013 | 784 | 2013 |
Inhibition of biosynthesis of polyisoprenol sugars in chick embryo microsomes by tunicamycin A Takatsuki, K Kohno, G Tamura Agricultural and Biological Chemistry 39 (10), 2089-2091, 1975 | 595 | 1975 |
Diphtheria toxin receptor–mediated conditional and targeted cell ablation in transgenic mice M Saito, T Iwawaki, C Taya, H Yonekawa, M Noda, Y Inui, E Mekada, ... Nature biotechnology 19 (8), 746-750, 2001 | 572 | 2001 |
S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP K Normington, K Kohno, Y Kozutsumi, MJ Gething, J Sambrook Cell 57 (7), 1223-1236, 1989 | 517 | 1989 |
A 22 bp cis-acting element is necessary and sufficient for the induction for the yeast KAR2(BiP) gene by unfolded proteins JS K. Mori, A. Sant, K. Kohno, K. Normington, M.-J. Gething EMBO Journal 11, 2583-2593, 1992 | 471 | 1992 |
Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. N Terada, HR Patel, K Takase, K Kohno, AC Nairn, EW Gelfand Proceedings of the national academy of sciences 91 (24), 11477-11481, 1994 | 468 | 1994 |
A transgenic mouse model for monitoring endoplasmic reticulum stress T Iwawaki, R Akai, K Kohno, M Miura Nature medicine 10 (1), 98-102, 2004 | 466 | 2004 |
The promoter region of the yeast KAR2(BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum K Kohno, K., Normington, K., Sambrook, J., Gething, M.-J., and Mori Molecular and Cellular Biology 13, 877-890, 1993 | 437 | 1993 |
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability T Iwawaki, R Akai, S Yamanaka, K Kohno Proceedings of the National Academy of Sciences 106 (39), 16657-16662, 2009 | 433 | 2009 |
Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast K Okamura, Y Kimata, H Higashio, A Tsuru, K Kohno Biochemical and biophysical research communications 279 (2), 445-450, 2000 | 423 | 2000 |
Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress T Iwawaki, A Hosoda, T Okuda, Y Kamigori, C Nomura-Furuwatari, ... Nature cell biology 3 (2), 158-164, 2001 | 380 | 2001 |
Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins Y Kimata, Y Ishiwata-Kimata, T Ito, A Hirata, T Suzuki, D Oikawa, ... The Journal of cell biology 179 (1), 75-86, 2007 | 369 | 2007 |
A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1 Y Kimata, D Oikawa, Y Shimizu, Y Ishiwata-Kimata, K Kohno The Journal of cell biology 167 (3), 445-456, 2004 | 350 | 2004 |
Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury M Abematsu, K Tsujimura, M Yamano, M Saito, K Kohno, J Kohyama, ... The Journal of clinical investigation 120 (9), 3255-3266, 2010 | 340 | 2010 |
Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways T Promlek, Y Ishiwata-Kimata, M Shido, M Sakuramoto, K Kohno, ... Molecular biology of the cell 22 (18), 3520-3532, 2011 | 296 | 2011 |
Severity and frequency of proximal tubule injury determines renal prognosis K Takaori, J Nakamura, S Yamamoto, H Nakata, Y Sato, M Takase, ... Journal of the American Society of Nephrology 27 (8), 2393-2406, 2016 | 276 | 2016 |