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| Transcription factors activate genes through the phase-separation capacity of their activation domains A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ... Cell 175 (7), 1842-1855. e16, 2018 | 1450 | 2018 |
| Mediator and RNA polymerase II clusters associate in transcription-dependent condensates WK Cho, JH Spille, M Hecht, C Lee, C Li, V Grube, II Cisse Science 361 (6400), 412-415, 2018 | 1156 | 2018 |
| Activation of proto-oncogenes by disruption of chromosome neighborhoods D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ... Science 351 (6280), 1454-1458, 2016 | 1088 | 2016 |
| YY1 is a structural regulator of enhancer-promoter loops AS Weintraub, CH Li, AV Zamudio, AA Sigova, NM Hannett, DS Day, ... Cell 171 (7), 1573-1588. e28, 2017 | 908 | 2017 |
| Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ... Cell 172 (5), 979-992. e6, 2018 | 472 | 2018 |
| Partitioning of cancer therapeutics in nuclear condensates IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ... Science 368 (6497), 1386-1392, 2020 | 352 | 2020 |
| Mediator condensates localize signaling factors to key cell identity genes AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ... Molecular Cell 76 (5), 753-766. e6, 2019 | 215 | 2019 |
| MeCP2 links heterochromatin condensates and neurodevelopmental disease CH Li, EL Coffey, A Dall’Agnese, NM Hannett, X Tang, JE Henninger, ... Nature, 1-8, 2020 | 152 | 2020 |
| Engineering of a histone-recognition domain in Dnmt3a alters the epigenetic landscape and phenotypic features of mouse ESCs KM Noh, H Wang, HR Kim, W Wenderski, F Fang, CH Li, S Dewell, ... Molecular cell 59 (1), 89-103, 2015 | 97 | 2015 |
| Small genomic insertions form enhancers that misregulate oncogenes BJ Abraham, D Hnisz, AS Weintraub, N Kwiatkowski, CH Li, Z Li, ... Nature communications 8, 14385, 2017 | 96 | 2017 |
| Chromatin kinases act on transcription factors and histone tails in regulation of inducible transcription SZ Josefowicz, M Shimada, A Armache, CH Li, RM Miller, S Lin, A Yang, ... Molecular cell 64 (2), 347-361, 2016 | 74 | 2016 |
| Differential cofactor dependencies define distinct types of human enhancers C Neumayr, V Haberle, L Serebreni, K Karner, O Hendy, A Boija, ... Nature, 1-8, 2022 | 67 | 2022 |
| Regulation and dysregulation of chromosome structure in cancer D Hnisz, J Schuijers, CH Li, RA Young Annual Review of Cancer Biology 2, 21-40, 2018 | 39 | 2018 |
| Multiplex epigenome editing of MECP2 to rescue Rett syndrome neurons J Qian, X Guan, B Xie, C Xu, J Niu, X Tang, CH Li, HM Colecraft, ... Science Translational Medicine 15 (679), eadd4666, 2023 | 38 | 2023 |
| Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription S Pomplun, M Jbara, CK Schissel, S Wilson Hawken, A Boija, C Li, I Klein, ... ACS Central Science, 2021 | 22 | 2021 |
| Methods of altering gene expression by perturbing transcription factor multimers that structure regulatory loops RA Young, AS Weintraub, CH Li, AA Sigova US Patent App. 16/476,868, 2019 | 3* | 2019 |
| Three-dimensional gene regulatory landscapes in normal and cancer cells BJ Abraham, YE Guo, D Hnisz, CH Li, AS Weintraub, DS Day, J Schuijers, ... Cancer Research 78 (13 Supplement), 971-971, 2018 | | 2018 |