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CJ Omiecinski
CJ Omiecinski
Emeritus Professor of Veterinary & Biomedical Sciences, Penn State University
Geverifieerd e-mailadres voor psu.edu
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The molecular basis of the human serum paraoxonase activity polymorphism
R Humbert, DA Adler, CM Disteche, C Hassett, CJ Omiecinski, ...
Nature Genetics 3 (1), 73-76, 1993
11211993
Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling
BC DiNatale, IA Murray, JC Schroeder, CA Flaveny, TS Lahoti, ...
Toxicological sciences 115 (1), 89-97, 2010
6642010
Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants
C Hassett, L Aicher, JS Sidhu, CJ Omiecinski
Human Molecular Genetics 3 (3), 421-428, 1994
6191994
Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix
EG Schuetz, D Li, CJ Omiecinski, U Muller‐Eberhard, HK Kleinman, ...
Journal of cellular physiology 134 (3), 309-323, 1988
5801988
Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities
CJ Omiecinski, JP Vanden Heuvel, GH Perdew, JM Peters
Toxicological sciences 120 (suppl_1), S49-S75, 2011
4912011
Human hepatic microsomal epoxide hydrolase: comparative analysis of polymorphic expression
C Hassett, J Lin, CL Carty, EM Laurenzana, CJ Omiecinski
Archives of Biochemistry and Biophysics 337 (2), 275-283, 1997
4111997
Epoxide hydrolases: biochemistry and molecular biology
AJ Fretland, CJ Omiecinski
Chemico-Biological Interactions 129 (1-2), 41-59, 2000
3832000
Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence
C Hassett, RJ Richter, R Humbert, C Chapline, JW Crabb, CJ Omiecinski, ...
Biochemistry 30 (42), 10141-10149, 1991
3631991
Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers
SR Faucette, TC Zhang, R Moore, T Sueyoshi, CJ Omiecinski, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 72-80, 2007
3392007
The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor
JC Schroeder, BC DiNatale, IA Murray, CA Flaveny, Q Liu, ...
Biochemistry 49 (2), 393-400, 2010
3262010
Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR …
CR Elcombe, RC Peffer, DC Wolf, J Bailey, R Bars, D Bell, RC Cattley, ...
Critical Reviews in Toxicology 44 (1), 64-82, 2014
2572014
Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction
CJ Omiecinski, CA Redlich, P Costa
Cancer Research 50 (14), 4315-4321, 1990
2561990
Concise review of the cytochrome P450s and their roles in toxicology.
CJ Omiecinski, RP Remmel, VP Hosagrahara
Toxicological Sciences 48 (2), 151-156, 1999
2281999
A Universal Approach to the Expression of Human and Rabbit Cytochrome P450s of the 2C Subfamily inEscherichia coli
TH Richardson, F Jung, KJ Griffin, M Wester, JL Raucy, B Kemper, ...
Archives of Biochemistry and Biophysics 323 (1), 87-96, 1995
1931995
Regiospecific expression of cytochrome P‐450s and microsomal epoxide hydrolase in human brain tissue
FM Farin, CJ Omiecinski
Journal of Toxicology and Environmental Health, Part A Current Issues 40 (2 …, 1993
1781993
Influence of extracellular matrix overlay on phenobarbital-mediated induction of CYP2B1, 2B2, and 3A1 genes in primary adult rat hepatocyte culture
JS Sidhu, FM Farin, CJ Omiecinski
Archives of Biochemistry and Biophysics 301 (1), 103-113, 1993
1741993
Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues
KM Olsavsky, JL Page, MC Johnson, H Zarbl, SC Strom, CJ Omiecinski
Toxicology and Applied Pharmacology 222 (1), 42-56, 2007
1612007
Human and rabbit paraoxonases: purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification
CE Furlong, LG Costa, C Hassett, RJ Richter, JA Sundstrom, DA Adler, ...
Chemico-Biological Interactions 87 (1-3), 35-48, 1993
1601993
Phenobarbital induction of rat liver cytochromes P-450b and P-450e. Quantitation of specific RNAs by hybridization to synthetic oligodeoxyribonucleotide probes.
CJ Omiecinski, FG Walz Jr, GP Vlasuk
Journal of Biological Chemistry 260 (6), 3247-3250, 1985
1591985
Alternatively spliced isoforms of the human constitutive androstane receptor
SS Auerbach, R Ramsden, MA Stoner, C Verlinde, C Hassett, ...
Nucleic Acids Research 31 (12), 3194-3207, 2003
1572003
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