Obserwuj
Brian Dougherty
Brian Dougherty
Executive Director, AstraZeneca
Zweryfikowany adres z astrazeneca.com
Tytuł
Cytowane przez
Cytowane przez
Rok
Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd
RD Fleischmann, MD Adams, O White, RA Clayton, EF Kirkness, ...
science 269 (5223), 496-512, 1995
78961995
The complete genome sequence of the gastric pathogen Helicobacter pylori
JF Tomb, O White, AR Kerlavage, RA Clayton, GG Sutton, ...
Nature 388 (6642), 539-547, 1997
44101997
The Minimal Gene Complement of Mycoplasma genitalium
CM Fraser, JD Gocayne, O White, MD Adams, RA Clayton, ...
Science 270 (5235), 397-404, 1995
34391995
Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii
CJ Bult, O White, GJ Olsen, L Zhou, RD Fleischmann, GG Sutton, ...
Science 273 (5278), 1058-1073, 1996
33271996
Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi
CM Fraser, S Casjens, WM Huang, GG Sutton, R Clayton, R Lathigra, ...
Nature 390 (6660), 580-586, 1997
26751997
Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised …
J Ledermann, P Harter, C Gourley, M Friedlander, I Vergote, G Rustin, ...
The lancet oncology 15 (8), 852-861, 2014
17552014
The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus
HP Klenk, RA Clayton, JF Tomb, O White, KE Nelson, KA Ketchum, ...
Nature 390 (6658), 364-370, 1997
17331997
Complete genome sequence of a virulent isolate of Streptococcus pneumoniae
H Tettelin, KE Nelson, IT Paulsen, JA Eisen, TD Read, S Peterson, ...
Science 293 (5529), 498-506, 2001
16852001
Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M
KS Thress, CP Paweletz, E Felip, BC Cho, D Stetson, B Dougherty, Z Lai, ...
Nature medicine 21 (6), 560-562, 2015
15542015
Complete genome sequence of Neisseria meningitidis serogroup B strain MC58
H Tettelin, NJ Saunders, J Heidelberg, AC Jeffries, KE Nelson, JA Eisen, ...
Science 287 (5459), 1809-1815, 2000
14122000
Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis
IT Paulsen, L Banerjei, GSA Myers, KE Nelson, R Seshadri, TD Read, ...
Science 299 (5615), 2071-2074, 2003
11222003
VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research
Z Lai, A Markovets, M Ahdesmaki, B Chapman, O Hofmann, R McEwen, ...
Nucleic acids research 44 (11), e108-e108, 2016
8162016
Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial
AM Oza, D Cibula, AO Benzaquen, C Poole, RHJ Mathijssen, GS Sonke, ...
The lancet oncology 16 (1), 87-97, 2015
6352015
RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer
C Cruz, M Castroviejo-Bermejo, S Gutiérrez-Enríquez, A Llop-Guevara, ...
Annals of Oncology 29 (5), 1203-1210, 2018
3702018
Capivasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer: the PAKT trial
P Schmid, J Abraham, S Chan, D Wheatley, AM Brunt, G Nemsadze, ...
Journal of Clinical Oncology 38 (5), 423-433, 2020
3282020
Acquired resistance to the mutant-selective EGFR inhibitor AZD9291 is associated with increased dependence on RAS signaling in preclinical models
CA Eberlein, D Stetson, AA Markovets, KJ Al-Kadhimi, Z Lai, PR Fisher, ...
Cancer research 75 (12), 2489-2500, 2015
3182015
Frequency and distribution of DNA uptake signal sequences in the Haemophilus influenzae Rd genome
HO Smith, JF Tomb, BA Dougherty, RD Fleischmann, JC Venter
Science 269 (5223), 538-540, 1995
3041995
AKT Inhibition in Solid Tumors With AKT1 Mutations
DM Hyman, LM Smyth, MTA Donoghue, SN Westin, PL Bedard, EJ Dean, ...
Journal of Clinical Oncology 35 (20), 2251-2259, 2017
2972017
Identification of 113 conserved essential genes using a high‐throughput gene disruption system in Streptococcus pneumoniae
JA Thanassi, SL Hartman‐Neumann, TJ Dougherty, BA Dougherty, ...
Nucleic acids research 30 (14), 3152-3162, 2002
2822002
Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes
DR Hodgson, BA Dougherty, Z Lai, A Fielding, L Grinsted, S Spencer, ...
British journal of cancer 119 (11), 1401-1409, 2018
2262018
Nie można teraz wykonać tej operacji. Spróbuj ponownie później.
Prace 1–20