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Kathryn Garner
Kathryn Garner
Head of Kidney Development at Newcells Biotech
Email confirmado em newcellsbiotech.co.uk
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Local inhibition of microRNA-24 improves reparative angiogenesis and left ventricle remodeling and function in mice with myocardial infarction
M Meloni, M Marchetti, K Garner, B Littlejohns, G Sala-Newby, ...
Molecular Therapy 21 (7), 1390-1402, 2013
1722013
RDGBα, a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction
S Yadav, K Garner, P Georgiev, M Li, E Gomez-Espinosa, A Panda, ...
Journal of cell science 128 (17), 3330-3344, 2015
942015
Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid
K Garner, AN Hunt, G Koster, P Somerharju, E Groves, M Li, P Raghu, ...
Journal of Biological Chemistry 287 (38), 32263-32276, 2012
922012
A novel mutation in the P2Y12 receptor and a function‐reducing polymorphism in protease‐activated receptor 1 in a patient with chronic bleeding
YM Patel, M Lordkipanidzé, GC Lowe, SP Nisar, K Garner, J Stockley, ...
Journal of Thrombosis and Haemostasis 12 (5), 716-725, 2014
572014
Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?
S Cockcroft, K Garner
Critical reviews in biochemistry and molecular biology 46 (2), 89-117, 2011
572011
Principles of Synthetic Biology
KL Garner
Essays in Biochemistry, EBC20200059, 2021
462021
Information transfer in gonadotropin-releasing hormone (GnRH) signaling: extracellular signal-regulated kinase (ERK)-mediated feedback loops control hormone sensing
KL Garner, RM Perrett, M Voliotis, C Bowsher, GR Pope, T Pham, ...
Journal of Biological Chemistry 291 (5), 2246-2259, 2016
442016
Mathematical modeling of gonadotropin-releasing hormone signaling
A Pratap, KL Garner, M Voliotis, K Tsaneva-Atanasova, CA McArdle
Molecular and cellular endocrinology 449, 42-55, 2017
382017
Potential role for phosphatidylinositol transfer protein (PITP) family in lipid transfer during phospholipase C signalling
S Cockcroft, K Garner
Advances in biological regulation 53 (3), 280-291, 2013
362013
The phosphatidylinositol transfer protein RdgBβ binds 14-3-3 via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein …
K Garner, M Li, N Ugwuanya, S Cockcroft
Biochemical Journal 439 (1), 97-111, 2011
362011
RdgBα reciprocally transfers PA and PI at ER–PM contact sites to maintain PI(4,5)P2 homoeostasis during phospholipase C signalling in Drosophila photoreceptors
S Cockcroft, K Garner, S Yadav, E Gomez-Espinoza, P Raghu
Biochemical Society Transactions 44 (1), 286-292, 2016
322016
Enhanced insulin receptor, but not PI3K, signalling protects podocytes from ER stress
KL Garner, VMS Betin, V Pinto, M Graham, E Abgueguen, M Barnes, ...
Scientific Reports 8 (1), 3902, 2018
252018
Information transfer via gonadotropin-releasing hormone receptors to ERK and NFAT: sensing GnRH and sensing dynamics
KL Garner, M Voliotis, H Alobaid, RM Perrett, T Pham, ...
Journal of the Endocrine Society 1 (4), 260-277, 2017
182017
14-3-3 protein and ATRAP bind to the soluble class IIB phosphatidylinositol transfer protein RdgBβ at distinct sites
S Cockcroft, K Garner
Biochemical Society Transactions 40 (2), 451-456, 2012
152012
Gonadotropin-releasing hormone signaling: An information theoretic approach
M Voliotis, KL Garner, H Alobaid, K Tsaneva-Atanasova, CA McArdle
Molecular and cellular endocrinology 463, 106-115, 2018
132018
High content imaging for monitoring signalling dynamics in single cells
KL Garner
Journal of Molecular Endocrinology 65 (4), R91-R100, 2020
62020
Exploring dynamics and noise in gonadotropin-releasing hormone (GnRH) Signaling
M Voliotis, KL Garner, H Alobaid, K Tsaneva-Atanasova, CA McArdle
Computational Cell Biology: Methods and Protocols, 405-429, 2018
52018
An information theoretic approach to insulin sensing by human kidney podocytes
RJP Pope, KL Garner, M Voliotis, AC Lay, VMS Betin, ...
Molecular and Cellular Endocrinology 518, 110976, 2020
32020
A live cell high content imaging assay for monitoring large molecule uptake into aproximate proximal tubule epithelial cells via megalin and cubilin
J Lowe, B Coker, K Pye, C Brown, K Garner
Drug Metabolism and Pharmacokinetics 55, 100856, 2024
2024
Developing predictive in vitro Glomerulus, Proximal Tubule and Loop of Henle renal cell model platforms to investigate the renal uptake and nephrotoxic liability of Large Molecules
C BROWN, K PYE, R LIANG, J LOWE, J OGDEN, K GARNER
日本毒性学会学術年会 第 51 回日本毒性学会学術年会, P-352, 2024
2024
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