Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance D Ge, J Fellay, AJ Thompson, JS Simon, KV Shianna, TJ Urban, ... Nature 461 (7262), 399-401, 2009 | 4548 | 2009 |
Large recurrent microdeletions associated with schizophrenia H Stefansson, D Rujescu, S Cichon, OPH Pietiläinen, A Ingason, ... nature 455 (7210), 232-236, 2008 | 3668* | 2008 |
A whole-genome association study of major determinants for host control of HIV-1 J Fellay, KV Shianna, D Ge, S Colombo, B Ledergerber, M Weale, ... science 317 (5840), 944-947, 2007 | 1518 | 2007 |
HLA-A* 3101 and carbamazepine-induced hypersensitivity reactions in Europeans M McCormack, A Alfirevic, S Bourgeois, JJ Farrell, D Kasperavičiūtė, ... New England Journal of Medicine 364 (12), 1134-1143, 2011 | 1106 | 2011 |
Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus AJ Thompson, AJ Muir, MS Sulkowski, D Ge, J Fellay, KV Shianna, ... Gastroenterology 139 (1), 120-129. e18, 2010 | 970 | 2010 |
Natural selection on EPAS1 (HIF2α) associated with low hemoglobin concentration in Tibetan highlanders CM Beall, GL Cavalleri, L Deng, RC Elston, Y Gao, J Knight, C Li, JC Li, ... Proceedings of the National Academy of Sciences 107 (25), 11459-11464, 2010 | 927 | 2010 |
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci SG Pillai, D Ge, G Zhu, X Kong, KV Shianna, AC Need, S Feng, CP Hersh, ... PLoS genetics 5 (3), e1000421, 2009 | 851 | 2009 |
A genome-wide investigation of SNPs and CNVs in schizophrenia AC Need, D Ge, ME Weale, J Maia, S Feng, EL Heinzen, KV Shianna, ... PLoS genetics 5 (2), e1000373, 2009 | 570 | 2009 |
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C J Fellay, AJ Thompson, D Ge, CE Gumbs, TJ Urban, KV Shianna, LD Little, ... Nature 464 (7287), 405-408, 2010 | 552 | 2010 |
Clinical application of exome sequencing in undiagnosed genetic conditions AC Need, V Shashi, Y Hitomi, K Schoch, KV Shianna, MT McDonald, ... Journal of medical genetics 49 (6), 353-361, 2012 | 516 | 2012 |
Long-range LD can confound genome scans in admixed populations AL Price, ME Weale, N Patterson, SR Myers, AC Need, KV Shianna, D Ge, ... The American Journal of Human Genetics 83 (1), 132-135, 2008 | 487 | 2008 |
Common genetic variation and the control of HIV-1 in humans J Fellay, D Ge, KV Shianna, S Colombo, B Ledergerber, ET Cirulli, ... PLoS genetics 5 (12), e1000791, 2009 | 480 | 2009 |
IL28B genotype is associated with differential expression of intrahepatic interferon‐stimulated genes in patients with chronic hepatitis C TJ Urban, AJ Thompson, SS Bradrick, J Fellay, D Schuppan, KD Cronin, ... Hepatology 52 (6), 1888-1896, 2010 | 465 | 2010 |
Cold Urticaria, Immunodeficiency, and Autoimmunity Related to PLCG2 Deletions MJ Ombrello, EF Remmers, G Sun, AF Freeman, S Datta, P Torabi-Parizi, ... New England Journal of Medicine 366 (4), 330-338, 2012 | 443 | 2012 |
A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice HL Tillmann, AJ Thompson, K Patel, M Wiese, H Tenckhoff, HD Nischalke, ... Gastroenterology 139 (5), 1586-1592. e1, 2010 | 428 | 2010 |
De novo mutations in ATP1A3 cause alternating hemiplegia of childhood EL Heinzen, KJ Swoboda, Y Hitomi, F Gurrieri, S Nicole, B de Vries, ... Nature genetics 44 (9), 1030-1034, 2012 | 414 | 2012 |
An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response A Mangia, AJ Thompson, R Santoro, V Piazzolla, HL Tillmann, K Patel, ... Gastroenterology 139 (3), 821-827. e1, 2010 | 400 | 2010 |
Tissue-specific genetic control of splicing: implications for the study of complex traits EL Heinzen, D Ge, KD Cronin, JM Maia, KV Shianna, WN Gabriel, ... PLoS biology 6 (12), e1000001, 2008 | 308 | 2008 |
Rare deletions at 16p13. 11 predispose to a diverse spectrum of sporadic epilepsy syndromes EL Heinzen, RA Radtke, TJ Urban, GL Cavalleri, C Depondt, AC Need, ... The American Journal of Human Genetics 86 (5), 707-718, 2010 | 283 | 2010 |
Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients NI Rallón, S Naggie, JM Benito, J Medrano, C Restrepo, D Goldstein, ... Aids 24 (8), F23-F29, 2010 | 264 | 2010 |