Synthesis and structure− activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase SH Hwang, KM Wagner, C Morisseau, JY Liu, H Dong, AT Wecksler, ... Journal of medicinal chemistry 54 (8), 3037-3050, 2011 | 181 | 2011 |
Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II–dependent hypertension A Ulu, TR Harris, C Morisseau, C Miyabe, H Inoue, G Schuster, H Dong, ... Journal of cardiovascular pharmacology 62 (3), 285-297, 2013 | 138 | 2013 |
Comparison of free serum oxylipin concentrations in hyper-vs. normolipidemic men JP Schuchardt, S Schmidt, G Kressel, H Dong, I Willenberg, BD Hammock, ... Prostaglandins, Leukotrienes and Essential Fatty Acids 89 (1), 19-29, 2013 | 113 | 2013 |
An Omega-3 Epoxide of Docosahexaenoic Acid Lowers Blood Pressure in Angiotensin-II–Dependent Hypertension A Ulu, KSS Lee, C Miyabe, J Yang, BG Hammock, H Dong, BD Hammock Journal of cardiovascular pharmacology 64 (1), 87-99, 2014 | 103 | 2014 |
Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy KSS Lee, JY Liu, KM Wagner, S Pakhomova, H Dong, C Morisseau, ... Journal of medicinal chemistry 57 (16), 7016-7030, 2014 | 102 | 2014 |
Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice TR Harris, A Bettaieb, S Kodani, H Dong, R Myers, N Chiamvimonvat, ... Toxicology and applied pharmacology 286 (2), 102-111, 2015 | 92 | 2015 |
Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis AGP Guedes, C Morisseau, A Sole, JHN Soares, A Ulu, H Dong, ... Veterinary anaesthesia and analgesia 40 (4), 440-448, 2013 | 85 | 2013 |
Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys A Ulu, SE Appt, C Morisseau, SH Hwang, PD Jones, TE Rose, H Dong, ... British journal of pharmacology 165 (5), 1401-1412, 2012 | 75 | 2012 |
Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models K Wagner, B Inceoglu, H Dong, J Yang, SH Hwang, P Jones, C Morisseau, ... European journal of pharmacology 700 (1-3), 93-101, 2013 | 74 | 2013 |
Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids C Morisseau, NH Schebb, H Dong, A Ulu, PA Aronov, BD Hammock Biochemical and biophysical research communications 419 (4), 796-800, 2012 | 69 | 2012 |
Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice A Frolov, L Yang, H Dong, BD Hammock, LJ Crofford Prostaglandins, Leukotrienes and Essential Fatty Acids 89 (5), 351-358, 2013 | 66 | 2013 |
Soluble epoxide hydrolase gene deficiency or inhibition attenuates chronic active inflammatory bowel disease in IL-10 (−/−) mice W Zhang, AL Yang, J Liao, H Li, H Dong, YT Chung, H Bai, ... Digestive diseases and sciences 57, 2580-2591, 2012 | 65 | 2012 |
Use of a soluble epoxide hydrolase inhibitor in smoke-induced chronic obstructive pulmonary disease L Wang, J Yang, L Guo, D Uyeminami, H Dong, BD Hammock, ... American journal of respiratory cell and molecular biology 46 (5), 614-622, 2012 | 60 | 2012 |
Redox Regulation of Soluble Epoxide Hydrolase by 15-Deoxy-Δ-Prostaglandin J2 Controls Coronary Hypoxic Vasodilation RL Charles, JR Burgoyne, M Mayr, SM Weldon, N Hubner, H Dong, ... Circulation research 108 (3), 324-334, 2011 | 59 | 2011 |
Soluble epoxide hydrolase inhibitor attenuates inflammation and airway hyperresponsiveness in mice J Yang, J Bratt, L Franzi, JY Liu, G Zhang, AA Zeki, CFA Vogel, K Williams, ... American journal of respiratory cell and molecular biology 52 (1), 46-55, 2015 | 57 | 2015 |
Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways KSS Lee, J Yang, J Niu, CJ Ng, KM Wagner, H Dong, SD Kodani, D Wan, ... ACS central science 5 (9), 1614-1624, 2019 | 54 | 2019 |
Cardioprotection by controlling hyperamylinemia in a “humanized” diabetic rat model S Despa, S Sharma, TR Harris, H Dong, N Li, N Chiamvimonvat, ... Journal of the American Heart Association 3 (4), e001015, 2014 | 51 | 2014 |
Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation [S] C Morisseau, AT Wecksler, C Deng, H Dong, J Yang, KSS Lee, ... Journal of lipid research 55 (6), 1131-1138, 2014 | 51 | 2014 |
Drug effects on the electrochemical detection of norepinephrine with carbon fiber and diamond microelectrodes H Dong, S Wang, A Liu, JJ Galligan, GM Swain Journal of Electroanalytical Chemistry 632 (1-2), 20-29, 2009 | 49 | 2009 |
Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice W Zhang, H Li, HUA Dong, JIE Liao, BD Hammock, GY Yang Anticancer research 33 (12), 5261-5271, 2013 | 45 | 2013 |