Highly conserved protective epitopes on influenza B viruses C Dreyfus, NS Laursen, T Kwaks, D Zuijdgeest, R Khayat, DC Ekiert, ... Science 337 (6100), 1343-1348, 2012 | 830 | 2012 |
HIV-1 neutralizing antibodies induced by native-like envelope trimers RW Sanders, MJ van Gils, R Derking, D Sok, TJ Ketas, JA Burger, ... Science 349 (6244), 2015 | 546 | 2015 |
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ... Nature 515 (7525), 138-142, 2014 | 516 | 2014 |
Cross-neutralization of influenza A viruses mediated by a single antibody loop DC Ekiert, AK Kashyap, J Steel, A Rubrum, G Bhabha, R Khayat, JH Lee, ... Nature 489 (7417), 526-532, 2012 | 502 | 2012 |
Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer JH Lee, G Ozorowski, AB Ward Science 351 (6277), 1043-1048, 2016 | 476 | 2016 |
Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers E Falkowska, KM Le, A Ramos, KJ Doores, JH Lee, C Blattner, A Ramirez, ... Immunity 40 (5), 657-668, 2014 | 469 | 2014 |
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 L Kong, JH Lee, KJ Doores, CD Murin, JP Julien, R McBride, Y Liu, ... Nature structural & molecular biology 20 (7), 796-803, 2013 | 412 | 2013 |
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans JP Julien, D Sok, R Khayat, JH Lee, KJ Doores, LM Walker, A Ramos, ... PLoS pathogens 9 (5), e1003342, 2013 | 409 | 2013 |
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers C Blattner, JH Lee, K Sliepen, R Derking, E Falkowska, AT de la Peña, ... Immunity 40 (5), 669-680, 2014 | 398 | 2014 |
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex D Sok, MJ van Gils, M Pauthner, JP Julien, KL Saye-Francisco, J Hsueh, ... Proceedings of the National Academy of Sciences 111 (49), 17624-17629, 2014 | 381 | 2014 |
Precursor frequency and affinity determine B cell competitive fitness in germinal centers, tested with germline-targeting HIV vaccine immunogens RK Abbott, JH Lee, S Menis, P Skog, M Rossi, T Ota, DW Kulp, D Bhullar, ... Immunity 48 (1), 133-146. e6, 2018 | 309 | 2018 |
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9 JP Julien, JH Lee, A Cupo, CD Murin, R Derking, S Hoffenberg, ... Proceedings of the National Academy of Sciences 110 (11), 4351-4356, 2013 | 308 | 2013 |
Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein AJ Behrens, S Vasiljevic, LK Pritchard, DJ Harvey, RS Andev, SA Krumm, ... Cell reports 14 (11), 2695-2706, 2016 | 272 | 2016 |
Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike L Scharf, JF Scheid, JH Lee, AP West Jr, C Chen, H Gao, ... Cell reports 7 (3), 785-795, 2014 | 256 | 2014 |
A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure JH Lee, R Andrabi, CY Su, A Yasmeen, JP Julien, L Kong, NC Wu, ... Immunity 46 (4), 690-702, 2017 | 245 | 2017 |
Affinity maturation of a potent family of HIV antibodies is primarily focused on accommodating or avoiding glycans F Garces, JH Lee, N de Val, AT de la Pena, L Kong, C Puchades, Y Hua, ... Immunity 43 (6), 1053-1063, 2015 | 221 | 2015 |
Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans F Garces, JH Lee, N de Val, AT de la Pena, L Kong, C Puchades, Y Hua, ... Immunity 43 (6), 1053-1063, 2015 | 221 | 2015 |
Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation RP Ringe, RW Sanders, A Yasmeen, HJ Kim, JH Lee, A Cupo, J Korzun, ... Proceedings of the National Academy of Sciences 110 (45), 18256-18261, 2013 | 215 | 2013 |
Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem C Havenar‐Daughton, JH Lee, S Crotty Immunological Reviews 275 (1), 49-61, 2017 | 177 | 2017 |
A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans D Sok, M Pauthner, B Briney, JH Lee, KL Saye-Francisco, J Hsueh, ... Immunity 45 (1), 31-45, 2016 | 149 | 2016 |