Three-Dimensional Folding and Functional Organization Principles of the Drosophila Genome T Sexton, E Yaffe, E Kenigsberg, F Bantignies, B Leblanc, M Hoichman, ... Cell, 2012 | 2077 | 2012 |
Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types DA Jaitin, E Kenigsberg, H Keren-Shaul, N Elefant, F Paul, I Zaretsky, ... Science 343 (6172), 776-779, 2014 | 1959 | 2014 |
Immunology of COVID-19: current state of the science N Vabret, GJ Britton, C Gruber, S Hegde, J Kim, M Kuksin, R Levantovsky, ... Immunity 52 (6), 910-941, 2020 | 1883 | 2020 |
Transcriptional heterogeneity and lineage commitment in myeloid progenitors F Paul, Y Arkin, A Giladi, DA Jaitin, E Kenigsberg, H Keren-Shaul, ... Cell 163 (7), 1663-1677, 2015 | 1169 | 2015 |
Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy JC Martin, C Chang, G Boschetti, R Ungaro, M Giri, JA Grout, K Gettler, ... Cell 178 (6), 1493-1508. e20, 2019 | 657 | 2019 |
A conserved dendritic-cell regulatory program limits antitumour immunity B Maier, AM Leader, ST Chen, N Tung, C Chang, J LeBerichel, ... Nature 580 (7802), 257-262, 2020 | 648 | 2020 |
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells M Casanova-Acebes, E Dalla, AM Leader, J LeBerichel, J Nikolic, ... Nature, 1-7, 2021 | 381 | 2021 |
Serum Amyloid A Proteins Induce Pathogenic TH17 Cells and Promote Inflammatory Disease JY Lee, JA Hall, L Kroehling, L Wu, T Najar, HH Nguyen, WY Lin, ... Cell 180 (1), 79-91. e16, 2020 | 363 | 2020 |
MARS-seq2. 0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing H Keren-Shaul, E Kenigsberg, DA Jaitin, E David, F Paul, A Tanay, I Amit Nature protocols 14 (6), 1841, 2019 | 228 | 2019 |
DNA methylation disruption reshapes the hematopoietic differentiation landscape F Izzo, SC Lee, A Poran, R Chaligne, F Gaiti, B Gross, RR Murali, ... Nature Genetics 52 (4), 378-387, 2020 | 217 | 2020 |
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification AM Leader, JA Grout, BB Maier, BY Nabet, MD Park, A Tabachnikova, ... Cancer Cell, 2021 | 214 | 2021 |
Primate CpG islands are maintained by heterogeneous evolutionary regimes involving minimal selection NM Cohen, E Kenigsberg, A Tanay Cell 145 (5), 773-786, 2011 | 164 | 2011 |
Intestinal host response to SARS-CoV-2 infection and COVID-19 outcomes in patients with gastrointestinal symptoms AE Livanos, D Jha, F Cossarini, AS Gonzalez-Reiche, M Tokuyama, ... Gastroenterology, 2021 | 154 | 2021 |
Spatial positioning and matrix programs of cancer-associated fibroblasts promote T-cell exclusion in human lung tumors JA Grout, P Sirven, AM Leader, S Maskey, E Hector, I Puisieux, F Steffan, ... Cancer Discovery 12 (11), 2606-2625, 2022 | 128 | 2022 |
Altering Sphingolipid Metabolism Attenuates Cell Death and Inflammatory Response after Myocardial Infarction Y Hadas, AS Vincek, E Youssef, MM Żak, E Chepurko, N Sultana, ... Circulation 141 (11), 916-930, 2020 | 115 | 2020 |
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity M Uzzan, JC Martin, L Mesin, AE Livanos, T Castro-Dopico, R Huang, ... Nature medicine 28 (4), 766-779, 2022 | 107 | 2022 |
Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma A Magen, P Hamon, N Fiaschi, BY Soong, MD Park, R Mattiuz, E Humblin, ... Nature medicine 29 (6), 1389-1399, 2023 | 103 | 2023 |
A myeloid–stromal niche and gp130 rescue in NOD2-driven Crohn’s disease S Nayar, JK Morrison, M Giri, K Gettler, L Chuang, LA Walker, HM Ko, ... Nature 593 (7858), 275-281, 2021 | 88 | 2021 |
TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer MD Park, I Reyes-Torres, J LeBerichel, P Hamon, NM LaMarche, ... Nature immunology 24 (5), 792-801, 2023 | 66 | 2023 |
A shift in lung macrophage composition is associated with COVID-19 severity and recovery ST Chen, MD Park, DM Del Valle, M Buckup, A Tabachnikova, ... Science Translational Medicine 14 (662), eabn5168, 2022 | 48 | 2022 |